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CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing

Abstract
Abstract The CRISPR–Cas system is a powerful genome editing tool that functions in a diverse array of organisms and cell types. The technology was initially developed to induce targeted mutations in DNA, but CRISPR–Cas has now been adapted to target nucleic acids for a range of purposes. CHOPCHOP is a web tool for identifying CRISPR–Cas single guide RNA (sgRNA) targets. In this major update of CHO...
Keywords
CRISPR
Biology
Genome editing
Computational biology
Subgenomic mRNA
Cas9
Genome
Genetics
Guide RNA
RNA
RNA editing
Gene
Sustainable Development Goals (SDG)
Industry, innovation and infrastructure


pdf file

CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing
pdf file

CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing

Abstract
Abstract The CRISPR–Cas system is a powerful genome editing tool that functions in a diverse array of organisms and cell types. The technology was initially developed to induce targeted mutations in DNA, but CRISPR–Cas has now been adapted to target nucleic acids for a range of purposes. CHOPCHOP is a web tool for identifying CRISPR–Cas single guide RNA (sgRNA) targets. In this major update of CHO...
Keywords
CRISPR
Biology
Genome editing
Computational biology
Subgenomic mRNA
Cas9
Genome
Genetics
Guide RNA
RNA
RNA editing
Gene
Sustainable Development Goals (SDG)
Industry, innovation and infrastructure


pdf file