Background: Telomere length and telomerase activity are crucial for cancer initiation and the survival of tumors.Telomere length is maintained by telomerase in 90% of human cancers, while 10% of cancers use an alternative mechanism of telomere lengthening termed (ALT).Another mechanism for Cancer cells is through activating or up-regulating the normally silent human TERT gene (hTERT) that encodes ...
Background: Telomere length and telomerase activity are crucial for cancer initiation and the survival of tumors.Telomere length is maintained by telomerase in 90% of human cancers, while 10% of cancers use an alternative mechanism of telomere lengthening termed (ALT).Another mechanism for Cancer cells is through activating or up-regulating the normally silent human TERT gene (hTERT) that encodes ...