Evaluation of Pre-miRNA-146a rs2910164 Variations and sCD40 Ligand in Egyptian Patients with Rheumatoid Arthritis

The Medical Journal of Cairo University/The Medical Journal of Cairo University

FATMA H. ABDELRAOUF, M.D.; HOIYDA A. ABDEL RASOL, M.D., WALAA G. HOZAYEN, M.D.; HANAN HUSSEIN, M.D., ENGY EL KHATEEB, M.D.; WALID BAKEER, M.D., GOMAA ABDEL RAZEK, M.D.; WAEL M. ABDEL KHALEK, M.D., HEND H. TAMIM, M.D.

References:

40

Abstract

Background: Patients with Rheumatoid Arthritis (RA) are at greater risk of developing Cardiovascular (CV) events with higher rate of subsequent mortality.MicroRNAs (miR-NAs) such as MiR-146a are thought to have an important role in the pathogenesis of RA.CD40-CD40L interaction is potentially involved in atherogenesis and plaque rupture in RA, it can be a risk factor in development of accelerated v...

Subjects

Rheumatoid arthritis

microRNA

Medicine

Internal medicine

Immunology

Biology

Genetics

Gene

Sustainable Development Goals (SDG)

Good health and well-being

2021

Article

Open Access

Institution

The Department of Clinical & Chemical Pathology, Faculty of Medicine, Cairo University, Cairo1, The Department of Clinical Pathology, Faculty of Medicine, Fayoum University, Fayoum2, The Department of Chemistry Division of Biochemistry, Faculty of Science3 and The Department of Biotechnology & Life Sciences, Faculty of Postgraduate Studies for Advanced Sciences (PSAS)4, Beni-Suef University, Beni-Suef, The Department of Rheumatology & Rehabilitation, Faculty of Medicine, Cairo University, Cairo5, The Department of Microbiology & Immunology, Faculty of Pharmacy, Beni-Suef and Nahda Universities, Beni-Suef 6, The Department of Cardiology, Faculty of Medicine, Fayoum University, Fayoum7 and The Department of Medical Biochemistry, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef 8, Egypt,

Cairo University,

Fayoum University

Publisher

Clinical Society of Cairo University

Journal Rank

0.135

DOI

https://doi.org/10.21608/mjcu.2021.168015

Language

en

Country

Egypt

Primary Source

Evaluation of Pre-miRNA-146a rs2910164 Variations and sCD40 Ligand in Egyptian Patients with Rheumatoid Arthritis

Primary Source

Evaluation of Pre-miRNA-146a rs2910164 Variations and sCD40 Ligand in Egyptian Patients with Rheumatoid Arthritis

The Medical Journal of Cairo University/The Medical Journal of Cairo University

FATMA H. ABDELRAOUF, M.D.; HOIYDA A. ABDEL RASOL, M.D., WALAA G. HOZAYEN, M.D.; HANAN HUSSEIN, M.D., ENGY EL KHATEEB, M.D.; WALID BAKEER, M.D., GOMAA ABDEL RAZEK, M.D.; WAEL M. ABDEL KHALEK, M.D., HEND H. TAMIM, M.D.

References:

40

Abstract

Background: Patients with Rheumatoid Arthritis (RA) are at greater risk of developing Cardiovascular (CV) events with higher rate of subsequent mortality.MicroRNAs (miR-NAs) such as MiR-146a are thought to have an important role in the pathogenesis of RA.CD40-CD40L interaction is potentially involved in atherogenesis and plaque rupture in RA, it can be a risk factor in development of accelerated v...