Search
Search
AI Chat
Recommendation
Reviewer
PDF Analysis
Projects
Sign in

Sign in to unlock AI Chat and more features

Recycling of modified H2A-H2B provides short-term memory of chromatin states

Cell

Valentin Flury, Nazaret Reverón-Gómez, Nicolas Alcaraz, Kathleen R. Stewart-Morgan, Alice Wenger, Robert J. Klose, Anja Groth

Citations:

75

References:

82

Abstract
Chromatin landscapes are disrupted during DNA replication and must be restored faithfully to maintain genome regulation and cell identity. The histone H3-H4 modification landscape is restored by parental histone recycling and modification of new histones. How DNA replication impacts on histone H2A-H2B is currently unknown. Here, we measure H2A-H2B modifications and H2A.Z during DNA replication and...
See More
Keywords
Biology
Chromatin
Epigenome
Histone
Histone code
Epigenetics
Histone H2B
DNA replication
Cell biology
Eukaryotic DNA replication
Histone H2A
Genetics
DNA
DNA methylation
Nucleosome
Gene
Gene expression
Sustainable Development Goals (SDG)
Life on land
2023
Article

Open Access

Institution

Biotech Research and Innovation Centre, University of Copenhagen, 2200 Copenhagen, Denmark, 

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, 2200 Copenhagen, Denmark, 

Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK

Publisher

Cell Press

2-Y Citation Average

37.59

DOI

https://doi.org/10.1016/j.cell.2023.01.007

Language

en

Country

Denmark, 

United Kingdom

Recycling of modified H2A-H2B provides short-term memory of chromatin states

Recycling of modified H2A-H2B provides short-term memory of chromatin states

Cell

Valentin Flury, Nazaret Reverón-Gómez, Nicolas Alcaraz, Kathleen R. Stewart-Morgan, Alice Wenger, Robert J. Klose, Anja Groth

Citations:

75

References:

82

Abstract
Chromatin landscapes are disrupted during DNA replication and must be restored faithfully to maintain genome regulation and cell identity. The histone H3-H4 modification landscape is restored by parental histone recycling and modification of new histones. How DNA replication impacts on histone H2A-H2B is currently unknown. Here, we measure H2A-H2B modifications and H2A.Z during DNA replication and...
See More
Keywords
Biology
Chromatin
Epigenome
Histone
Histone code
Epigenetics
Histone H2B
DNA replication
Cell biology
Eukaryotic DNA replication
Histone H2A
Genetics
DNA
DNA methylation
Nucleosome
Gene
Gene expression
Sustainable Development Goals (SDG)
Life on land
2023
Article

Open Access

Institution

Biotech Research and Innovation Centre, University of Copenhagen, 2200 Copenhagen, Denmark, 

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, 2200 Copenhagen, Denmark, 

Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK

Publisher

Cell Press

2-Y Citation Average

37.59

DOI

https://doi.org/10.1016/j.cell.2023.01.007

Language

en

Country

Denmark, 

United Kingdom