Bifonazole Loaded Transethosomal Gel: Formulation and Optimization by Box Behnken Design

Citations:

1

Abstract

This study was intended to develop and optimize the transethosomal gel of Bifonazole for the treatment of fungal infections. For the optimization purpose, Box-Behnken Design was used, and the concentration of soya lecithin, ethanol and sodium cholate were selected as independent variables. The individual and combined effects of independent variables were assessed on vesicle size, PDI and entrapmen...

Subjects

Box–Behnken design

Bifonazole

Chromatography

Chemistry

Response surface methodology

Biology

Microbiology

Antifungal

2023

Article

Institution

Department of Pharmaceutics, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to be University) Mangalore-575018, India,

Department of Pharmaceutics, Yenepoya Pharmacy College &amp

Journal Rank

0.353

DOI

https://doi.org/10.21608/bfsa.2023.239243.1932

Language

en

Country

India

Primary Source

Bifonazole Loaded Transethosomal Gel: Formulation and Optimization by Box Behnken Design

Primary Source

Bifonazole Loaded Transethosomal Gel: Formulation and Optimization by Box Behnken Design

Deleted Journal

Kshema ., Sandhya Vasanth, Sneh Priya

Citations:

1

Abstract

This study was intended to develop and optimize the transethosomal gel of Bifonazole for the treatment of fungal infections. For the optimization purpose, Box-Behnken Design was used, and the concentration of soya lecithin, ethanol and sodium cholate were selected as independent variables. The individual and combined effects of independent variables were assessed on vesicle size, PDI and entrapmen...