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Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain

Molecular Psychiatry

Orr Shahar, Alexander Botvinnik, Amit Shwartz, Elad Lerer, Peretz Golding, Alex Buko, Ethan Hamid, Dani Kahn, Miles Guralnick, Karin Blakolmer, Gilly Wolf, Amit Lotan, Leonard Lerer, Bernard Lerer, Tzuri Lifschytz

Citations:

17

References:

80

Abstract
Psilocybin, a naturally occurring, tryptamine alkaloid prodrug, is currently being investigated for the treatment of a range of psychiatric disorders. Preclinical reports suggest that the biological effects of psilocybin-containing mushroom extract or "full spectrum" (psychedelic) mushroom extract (PME), may differ from those of chemically synthesized psilocybin (PSIL). We compared the effects of ...
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Keywords
Psilocybin
Hallucinogen
Mushroom
Mushroom poisoning
Pharmacology
Neuroscience
Psychology
Chemistry
Medicine
Food science
Sustainable Development Goals (SDG)
Good health and well-being
2024
Article

Open Access

Institution

Biological Psychiatry Laboratory and Hadassah BrainLabs Center for Psychedelic Research, Hadassah Medical Center, Hebrew University, Jerusalem, Israel, 

Achva Academic College, Beer Tuvia, Israel

Publisher

Springer Nature

2-Y Citation Average

11.412

DOI

https://doi.org/10.1038/s41380-024-02477-w

Language

en

Country

Israel

pdf file
Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain
pdf file

Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain

Molecular Psychiatry

Orr Shahar, Alexander Botvinnik, Amit Shwartz, Elad Lerer, Peretz Golding, Alex Buko, Ethan Hamid, Dani Kahn, Miles Guralnick, Karin Blakolmer, Gilly Wolf, Amit Lotan, Leonard Lerer, Bernard Lerer, Tzuri Lifschytz

Citations:

17

References:

80

Abstract
Psilocybin, a naturally occurring, tryptamine alkaloid prodrug, is currently being investigated for the treatment of a range of psychiatric disorders. Preclinical reports suggest that the biological effects of psilocybin-containing mushroom extract or "full spectrum" (psychedelic) mushroom extract (PME), may differ from those of chemically synthesized psilocybin (PSIL). We compared the effects of ...
See More
View PDF
Keywords
Psilocybin
Hallucinogen
Mushroom
Mushroom poisoning
Pharmacology
Neuroscience
Psychology
Chemistry
Medicine
Food science
Sustainable Development Goals (SDG)
Good health and well-being
2024
Article

Open Access

Institution

Biological Psychiatry Laboratory and Hadassah BrainLabs Center for Psychedelic Research, Hadassah Medical Center, Hebrew University, Jerusalem, Israel, 

Achva Academic College, Beer Tuvia, Israel

Publisher

Springer Nature

2-Y Citation Average

11.412

DOI

https://doi.org/10.1038/s41380-024-02477-w

Language

en

Country

Israel

pdf file