Mechanical Allodynia and Thermal Hyperalgesia in Diabetic Mice and Neurodegenerative Changes in the Spinal Cord and Sciatic Nerves: Modulation by Topiramate
Background: Diabetes-related pathological alterations in body organs may take place due to immunological reactions and inflammatory/oxidative burden. Aim of Study: The current study aimed to test the neuropro-tective effect of topiramate in an animal model of peripheral di-abetic neuropathy (DN) and test its ability to suppress the spinal cord inflammatory burden and glial reactivity. Material and...
Mechanical Allodynia and Thermal Hyperalgesia in Diabetic Mice and Neurodegenerative Changes in the Spinal Cord and Sciatic Nerves: Modulation by Topiramate
Mechanical Allodynia and Thermal Hyperalgesia in Diabetic Mice and Neurodegenerative Changes in the Spinal Cord and Sciatic Nerves: Modulation by Topiramate
Background: Diabetes-related pathological alterations in body organs may take place due to immunological reactions and inflammatory/oxidative burden. Aim of Study: The current study aimed to test the neuropro-tective effect of topiramate in an animal model of peripheral di-abetic neuropathy (DN) and test its ability to suppress the spinal cord inflammatory burden and glial reactivity. Material and...