Background The false negative rate of alpha-fetoprotein (AFP) level alone may be as high as 40% for patients with early stage of hepatocellular carcinoma (HCC) and may be elevated in non-malignant chronic liver diseases and other malignancies. Glypican-3 (GPC-3) is a new tumor marker for HCC. Objective: Evaluation of the role of serum GPC-3 in the early diagnosis of HCC. Results: There was a highl...
Background The false negative rate of alpha-fetoprotein (AFP) level alone may be as high as 40% for patients with early stage of hepatocellular carcinoma (HCC) and may be elevated in non-malignant chronic liver diseases and other malignancies. Glypican-3 (GPC-3) is a new tumor marker for HCC. Objective: Evaluation of the role of serum GPC-3 in the early diagnosis of HCC. Results: There was a highl...