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New Quinolinyl Chalcones with Potential Antiplasmodial Activity: Synthesis and In Vivo Studies On Plasmodium Berghi

Abstract
Malaria remains a devastating parasitic disease of the tropics, with reported decreased sensitivity to all the available drugs.Spurred by the previous literature and computational studies against four plasmodium proteases, three quinolinyl chalcone derivatives; 3-prop-2-en-1-one (P4) and 3-(2-chloro-6-methoxyquinolin-3-yl)-1-(2, 3, 4-trimethoxyphenyl) prop-2-en-1-one (P5) were synthesized and eval...
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Keywords
In vivo
Plasmodium falciparum
Plasmodium (life cycle)
Virology
Malaria
Chemistry
Biology
Traditional medicine
Medicine
Computer science
Biotechnology
Immunology
Parasite hosting
World Wide Web
Sustainable Development Goals (SDG)
Zero hunger


pdf file

New Quinolinyl Chalcones with Potential Antiplasmodial Activity: Synthesis and In Vivo Studies On Plasmodium Berghi
pdf file

New Quinolinyl Chalcones with Potential Antiplasmodial Activity: Synthesis and In Vivo Studies On Plasmodium Berghi

Abstract
Malaria remains a devastating parasitic disease of the tropics, with reported decreased sensitivity to all the available drugs.Spurred by the previous literature and computational studies against four plasmodium proteases, three quinolinyl chalcone derivatives; 3-prop-2-en-1-one (P4) and 3-(2-chloro-6-methoxyquinolin-3-yl)-1-(2, 3, 4-trimethoxyphenyl) prop-2-en-1-one (P5) were synthesized and eval...
View PDF
Keywords
In vivo
Plasmodium falciparum
Plasmodium (life cycle)
Virology
Malaria
Chemistry
Biology
Traditional medicine
Medicine
Computer science
Biotechnology
Immunology
Parasite hosting
World Wide Web
Sustainable Development Goals (SDG)
Zero hunger


pdf file