Background: Multiple sclerosis (MS) is a neurodegenerative disease, and is considered a chronic inflammatory disease.Retinal nerve fiber layer (RNFL) thickness as a structural biomarker for axonal loss in MS. Objective:The aim of the present study was to assess the role of optical coherence tomography (OCT) in detecting RNFL in MS patients without history of optic neuritis and to correlate with di...