The current work was undertaken to evaluate in vitro the antimicrobial activity of two edible Mushrooms (Basidiomycetes & macrofungus), Pleurotus osteratus and Agaricus bisporus , either fresh or air dried were assyed using aqueous and organic solvents extracts.The assays were done against a panel of standard pathogenic bacteria and fungi.Agar well diffusion assay showed that gram (+ve) bacteria w...