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Potential COX2 mediated Therapeutic effect of Ciprofloxacin

Abstract
Fluoroquinolones (FQs) are broad-spectrum, synthetic antibiotics that inhibit bacterial DNA synthesis. FQs directly block DNA synthesis in the bacterial cell via inhibition the activity of two tetrameric, ATPdependent, homologous type II topoisomerase enzymes: topoisomerase II-called DNA gyrase and topoisomerase IV. FQs are also active against eukaryotic topoisomerase II. This property results in ...
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Keywords
Ciprofloxacin
Pharmacology
Medicine
Biology
Microbiology
Antibiotics


pdf file

Potential COX2 mediated Therapeutic effect of Ciprofloxacin
pdf file

Potential COX2 mediated Therapeutic effect of Ciprofloxacin

Abstract
Fluoroquinolones (FQs) are broad-spectrum, synthetic antibiotics that inhibit bacterial DNA synthesis. FQs directly block DNA synthesis in the bacterial cell via inhibition the activity of two tetrameric, ATPdependent, homologous type II topoisomerase enzymes: topoisomerase II-called DNA gyrase and topoisomerase IV. FQs are also active against eukaryotic topoisomerase II. This property results in ...
View PDF
Keywords
Ciprofloxacin
Pharmacology
Medicine
Biology
Microbiology
Antibiotics


pdf file
2023
Article

Open Access

Renal ischemia/reperfusion (IR) injury is characterized by an unexpected impairment of blood flow to the kidney. Azilsartan is an angiotensin receptor blocker that is approved for the management of hypertension. The present study aimed to investigate...