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Frequency of CD8+T lymphocyte expression in HCV induced Hepatocellular carcinoma

El-Minia Medical Bulletin

Amel Kamal Eldin, Lamiaa Ali, Mohammed Abd El Hakeem, Wael Abd El Ghany, Rana Ahmed

References:

12

Abstract
Hepatitis C in humans is a global public health problem that causes chronic viral hepatitis which progresses to liver cirrhosis and hepatocellular carcinoma(HCC).HCC is the most frequent primary liver malignancy and the third cause of cancer-related deaths.Alpha-fetoprotein (AFP) is the most practical and widely used serum biomarker for HCC diagnosis.This prospective study was carried out in the C...
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Keywords
Hepatocellular carcinoma
CD8
Cytotoxic T cell
Lymphocyte
T lymphocyte
Medicine
Cancer research
Immunology
Biology
Immune system
Genetics
In vitro
2020
Article

Open Access

Institution

Department of Clinical pathology, faculty of medicine, Minia university

2-Y Citation Average

0.16

DOI

https://doi.org/10.21608/mjmr.2022.221492

Language

en

Country

Egypt

pdf file
Frequency of CD8+T lymphocyte expression in HCV induced Hepatocellular carcinoma
pdf file

Frequency of CD8+T lymphocyte expression in HCV induced Hepatocellular carcinoma

El-Minia Medical Bulletin

Amel Kamal Eldin, Lamiaa Ali, Mohammed Abd El Hakeem, Wael Abd El Ghany, Rana Ahmed

References:

12

Abstract
Hepatitis C in humans is a global public health problem that causes chronic viral hepatitis which progresses to liver cirrhosis and hepatocellular carcinoma(HCC).HCC is the most frequent primary liver malignancy and the third cause of cancer-related deaths.Alpha-fetoprotein (AFP) is the most practical and widely used serum biomarker for HCC diagnosis.This prospective study was carried out in the C...
See More
View PDF
Keywords
Hepatocellular carcinoma
CD8
Cytotoxic T cell
Lymphocyte
T lymphocyte
Medicine
Cancer research
Immunology
Biology
Immune system
Genetics
In vitro
2020
Article

Open Access

Institution

Department of Clinical pathology, faculty of medicine, Minia university

2-Y Citation Average

0.16

DOI

https://doi.org/10.21608/mjmr.2022.221492

Language

en

Country

Egypt

pdf file
Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape

Cancer Research

Seng-Ryong Woo, Meghan E. Turnis, Monica V. Goldberg, Jaishree Bankoti, Mark Selby, Christopher J. Nirschl, Matthew L. Bettini, David M. Gravano, Peter Vogel, Chih Long Liu, Stephanie Tangsombatvisit, Joseph F. Grosso, George Netto, Matthew P. Smeltzer, Alcides Chaux, Paul J. Utz, Creg J. Workman, Drew M. Pardoll, Alan J. Korman, Charles G. Drake, Dario A.A. Vignali

2011
Article

Open Access

Inhibitory receptors on immune cells are pivotal regulators of immune escape in cancer. Among these inhibitory receptors, CTLA-4 (targeted clinically by ipilimumab) serves as a dominant off-switch while other receptors such as PD-1 and LAG-3 seem to ...