Nephrotoxicity of Patulin and its Modulation by Aqueous Green Tea Extract in Male Albino Rats

Nagwa Elsawi, Hisham Ismail, Ahmed Sayed, Soad Shaker Ali, Ahmed Khamis

Abstract

Patulin (PAT) is a major secondary metabolic mycotoxin produced by Penicillium that can contaminate food. Patulin forms an adduct when it interacts with amino acids that contain thiol groups; the creation of these adducts could represent the main toxic pathway of PAT. Catechins are a major component of green tea polyphenols. Polyphenols have many protective effects against chronic diseases. In thi...

View PDF

Keywords

Patulin

Nephrotoxicity

Aqueous extract

Aqueous solution

Traditional medicine

Pharmacology

Chemistry

Toxicology

Medicine

Biology

Kidney

Food science

Internal medicine

Mycotoxin

Organic chemistry

Sustainable Development Goals (SDG)

Zero hunger

2023

Article

Open Access

Institution

Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt.,

Chemistry Department, Faculty of Science, Minya University, Minya 61519, Egypt.,

Histology, Faculty of Medicine, Assiut University, Assiut 98467, Egypt.

2-Y Citation Average

0.354

DOI

https://doi.org/10.21608/sjsci.2023.226367.1106

Language

en

Country

Egypt

Nephrotoxicity of Patulin and its Modulation by Aqueous Green Tea Extract in Male Albino Rats

Deleted Journal

Nagwa Elsawi, Hisham Ismail, Ahmed Sayed, Soad Shaker Ali, Ahmed Khamis

Abstract

Patulin (PAT) is a major secondary metabolic mycotoxin produced by Penicillium that can contaminate food. Patulin forms an adduct when it interacts with amino acids that contain thiol groups; the creation of these adducts could represent the main toxic pathway of PAT. Catechins are a major component of green tea polyphenols. Polyphenols have many protective effects against chronic diseases. In thi...